CALL FOR PAPERS Mitochondrial Metabolism Growth restriction in the rat alters expression of metabolic genes during postnatal cardiac development in a sex-specific manner
نویسندگان
چکیده
Glenn D. Wadley, Glenn K. McConell, Craig A. Goodman, Andrew L. Siebel, Kerryn T. Westcott, and Mary E. Wlodek Department of Physiology, The University of Melbourne, Parkville, Victoria, Australia; Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria, Australia; Institute of Sport, Exercise and Active Living and the School of Biomedical and Health Sciences, Victoria University, Footscray, Victoria, Australia; Metabolic & Vascular Physiology Laboratory, Baker IDI Heart & Diabetes Institute, Prahran, Victoria, Australia; and Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin
منابع مشابه
Growth restriction in the rat alters expression of metabolic genes during postnatal cardiac development in a sex-specific manner.
This study investigated the impact of uteroplacental insufficiency and growth restriction on the expression of genes related to mitochondrial biogenesis, glucose transport, and antioxidant defenses in cardiac tissue at embryonic day 20 (E20) and postnatal days 1, 7, and 35 in male and female Wistar rats (8-10 per group). Bilateral uterine vessel ligation to induce growth restriction (Restricted...
متن کاملUteroplacental insufficiency and reducing litter size alters skeletal muscle mitochondrial biogenesis in a sex-specific manner in the adult rat.
Uteroplacental insufficiency has been shown to impair insulin action and glucose homeostasis in adult offspring and may act in part via altered mitochondrial biogenesis and lipid balance in skeletal muscle. Bilateral uterine vessel ligation to induce uteroplacental insufficiency in offspring (Restricted) or sham surgery was performed on day 18 of gestation in rats. To match the litter size of R...
متن کاملP75: Expression of GDNF Genes in the Cerebellum of Rat Neonate Born to Mother with Diabetes
Diabetes Mellitus as a common metabolic disorder in women of reproductive age is rising throughout the globe. Diabetes in pregnancy has various adverse outcomes on different organs development including the central nervous system (CNS) and it can cause learning deficits, behavioral problems and motor dysfunctions in the offspring. The cerebellum is a part of brain that coordinates voluntary mov...
متن کاملGene Expression Profile of CatSper3 and CatSper4 during Postnatal Development of Mouse Testis
Channel activities, particularly those of calcium channels, have vital roles in the process of sperm maturation, motility and sperm-egg interaction. A group of the recently discovered ion channels associated with these processes is four novel channel-like proteins known as CatSper (cation channel sperm) gene family. CatSper1 and CatSper2 show sperm specific expression patterns. However, neither...
متن کاملFungal Infection Alters Phosphate Level and Phosphatase Profiles in Arabidopsis
Phosphorus (P), in the form of phosphate ion (Pi), is a vital element contributing in biomolecule structures, metabolic reactions, signaling pathways and energy transfer within the living cells. The objective of the present study was to assess the influence of fungal infection on Pi metabolism in compare to the effects of phosphate stress in Arabidopsis. Quantification of total P contents showe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2013